Misfortune, as expected, brings discomfort with it (6)

I believe the answer is:

unease

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'it' is the definition.
The definition suggests a singular noun which matches the answer.

'misfortune as expected brings discomfort' is the wordplay.
'UNEASE' is hidden in amongst the letters.
However, I am uncertain how this is indicated.

'with' is the link.

Can you help me to learn more?

(Other definitions for unease that I've seen before include "State of anxiety" , "State of worry and lack of confidence" , "Anxiety, discontent" , "Disquiet" , "Discomfort or apprehension" .)

I've seen this clue in The Telegraph.

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