Misgivings about mixing liquor and ecstasy — it’s a gamble (6,2,5)
I believe the answer is:
double or quits
'a gamble' is the definition.
I don't know anything about this answer so I can't judge whether this works.
'misgivings about mixing liquor and ecstasy' is the wordplay.
'misgivings' becomes 'doubts' (I've seen this in another clue).
'about' means one lot of letters goes inside another.
'mixing' indicates an anagram.
'and' is a charade indicator (letters next to each other).
'ecstasy' becomes 'E' (informal term for the drug).
'liquor'+'e'='liquore'
'liquore' anagrammed gives 'leorqui'.
'doubts' going around 'leorqui' is 'DOUBLE OR QUITS'.
'it's' acts as a link.
Can you help me to learn more?
(Other definitions for double or quits that I've seen before include "Gambler's call to wager again the amount already owed" , "Gambling alternative" , "Offer to gamble the same again to cancel a debt" , "Gambling chance to increase or cancel 14 down" .)