Misguided carer keeps up initial dose of poison (6)
I believe the answer is:
curare
'dose of poison' is the definition.
'curare' can be an answer for 'poison' (I've seen this before). I'm not sure about the 'dose of' bit.
'misguided carer keeps up initial' is the wordplay.
'misguided' indicates an anagram (I've seen this in other clues).
'keeps' is an insertion indicator.
'initial' suggests taking the first letters.
The initial letter of 'up' is 'u'.
'carer' with letters rearranged gives 'crare'.
'crare' going around 'u' is 'CURARE'.
Can you help me to learn more?
(Other definitions for curare that I've seen before include "Poison applied to darts" , "Paralysing plant poison" , "Poison put on arrows" , "Poison used on darts" , "Arrow poison" .)