Misguidedly begin a jollification (5)
I believe the answer is:
binge
'a jollification' is the definition.
(binge is a kind of jollification)
'misguidedly begin' is the wordplay.
'misguidedly' is an anagram indicator.
'begin' with letters rearranged gives 'BINGE'.
(Other definitions for binge that I've seen before include "Indulge too much" , "Bout of excessive activity" , "A heavy drinking session" , "Period of excess" , "Bender" .)