Miss France leaves upset (3)
I believe the answer is:
ail
'upset' is the definition.
(thesaurus)
'miss france leaves' is the wordplay.
'miss' becomes 'fail' (failing is a kind of missing).
'france' becomes 'f'.
'leaves' is a deletion indicator.
'fail' with 'f' taken out is 'AIL'.
(Other definitions for ail that I've seen before include "Bother" , "Become unwell" , "Be unwell, feel poorly" , "upset" , "Cause to feel indisposed" .)