Miss opportunity to wrap up, heading off (4,3)
I believe the answer is:
lose out
'miss opportunity' is the definition.
'lose out' can be an answer for 'miss' (thesaurus). I'm unsure of the 'opportunity' bit.
'wrap up heading off' is the wordplay.
'wrap up' becomes 'lose' (I can't explain this - if you can you should believe this answer much more).
'heading' is a charade indicator (letters next to each other) (some letters go in front of or head others).
'off' becomes 'out'.
'lose'+'out'='LOSE OUT'
'to' is the link.
Can you help me to learn more?
(Other definitions for lose out that I've seen before include "Miss a possible benefit" , "Get overlooked" , "Suffer disadvantage" , "Finish at a disadvantage" , "Be deprived of an opportunity" .)