Mistake talking of home (4)
I believe the answer is:
gaff
'home' is the definition.
(I've seen this before)
'mistake talking' is the wordplay.
'mistake' becomes 'gaffe' (a gaffe is a mistake or error).
'talking' indicates a 'sounds like' (homophone) clue.
'gaffe' sounds like 'GAFF'.
'of' acts as a link.
(Other definitions for gaff that I've seen before include "Hook used to land fish" , "Spar" , "Iron hook for landing big fish" , "Blunder" , "Fishing spear" .)