Mistake, whichever way one looks at it (4)
I believe the answer is:
boob
This clue is a double definition.
'mistake' is the first definition.
(thesaurus)
'whichever way one looks at it' is the second definition.
(Other definitions for boob that I've seen before include "Mistake; breast (sl.)" , "Error" , "Embarrassing mistake" , "Slip" , "Blunder (colloq.)" .)