Mixed lone dose and relaxed (8)

I believe the answer is:

loosened

'relaxed' is the definition.
('loosen' can be a synonym of 'relax')

'mixed lone dose' is the wordplay.
'mixed' indicates anagramming the letters.
'lone'+'dose'='lonedose'
'lonedose' with letters rearranged gives 'LOOSENED'.

'and' acts as a link.

(Another definition for loosened that I've seen is " Made slack, eased as with grip".)

I've seen this clue in The Mirror.

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