Mobster leads goners with acute sense of anxiety to central Peru (8)
I believe the answer is:
gangster
'mobster' is the definition.
(I know that mobster can be written as gangster)
'sense of anxiety to central peru' is the wordplay.
'sense of' becomes 'g' (I can't justify this - if you can you should believe this answer much more).
'anxiety' becomes 'angst' (angst is a type of anxiety).
'to central' says to take the centre.
The centre of 'peru' is 'er'.
'g'+'angst'+'er'='GANGSTER'
'leads goners with acute' acts as a link.
I am not very happy about this link. Some or all of it may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for gangster that I've seen before include "Wise guy" , "Mafia man" , "Member of a band of criminals" , "Typical Cagney role" , "Organised criminal" .)