Mole from Homeland in full house (4)
I believe the answer is:
hand
'full house' is the definition.
(thesaurus)
'mole from homeland' is the wordplay.
'from' is a deletion indicator.
'homeland' with 'mole' taken out is 'HAND'.
'in' is the link.
(Other definitions for hand that I've seen before include "Fingered organ" , "Limb extremity" , "Clock pointer; labourer" , "Clock-pointer" , "Player's cards" .)