Mondrian and a painting of the BVM (5)
I believe the answer is:
pieta
'painting of the bvm' is the definition.
(artwork depicting the Blessed Virgin Mary)
'mondrian and a' is the wordplay.
'mondrian' becomes 'Piet' (painter Piet Mondrian is an example).
'and' means one lot of letters go next to another.
'piet'+'a'='PIETA'
(Other definitions for pieta that I've seen before include "religious picture?" , "Devotional painting" , "Sculpture of Mary with Christ's body" , "weeping figure" , "Statue of Virgin Mary" .)