More awful retsina drunk (7)
I believe the answer is:
nastier
'more awful' is the definition.
('nasty' can be similar in meaning to 'awful')
'retsina drunk' is the wordplay.
'drunk' is an anagram indicator.
'retsina' is an anagram of 'NASTIER'.
(Other definitions for nastier that I've seen before include "more awkward" , "more aggressive" , "becomes more unpleasant" , "More horrid" , "Less pleasant" .)