More inquisitive envoy's wife oddly ignored king (6)
I believe the answer is:
nosier
'more inquisitive' is the definition.
(nosy means overly inquisitive or curious)
'envoy's wife oddly ignored king' is the wordplay.
'oddly ignored' means one should take alternating letters (letters in odd-numbered positions removed).
'king' becomes 'R' (abbreviation for rex, king in Latin).
'envoys'+'wife'='envoyswife'
The alternating letters of 'envoyswife' are 'nosie'.
'nosie'+'r'='NOSIER'
(Other definitions for nosier that I've seen before include "More inquisitive" , "rather curious" , "comparatively curious" , "More curious, being senior" , "More curious in nasal way" .)