More unpleasant retsina circulated (7)
I believe the answer is:
nastier
'more unpleasant' is the definition.
('nasty' can be similar in meaning to 'unpleasant')
'retsina circulated' is the wordplay.
'circulated' indicates anagramming the letters.
'retsina' anagrammed gives 'NASTIER'.
(Other definitions for nastier that I've seen before include "more awkward" , "Less nice" , "More horrid" , "Retsina (anag) -- not so nice" , "Getting even worse" .)