Most direct route (7)
I believe the answer is:
beeline
'most direct route' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for beeline that I've seen before include "Make ........ for - go straight towards like honey collector" , "Straightest route" , "Straight route" , "Undeviating route" , "To make a -- for is to go without deviation" .)