Most horrible stain is dispersed by English saint (8)

I believe the answer is:

nastiest

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'most horrible' is the definition.
Both the answer and definition are superlative adjectives. Perhaps there's a link between them I don't understand?

'stain is dispersed by english saint' is the wordplay.
'is dispersed' indicates anagramming the letters.
'by' says to put letters next to each other.
'english' becomes 'E' (abbreviation).
'saint' becomes 'st'.
'stain' anagrammed gives 'nasti'.
'nasti'+'e'+'st'='NASTIEST'

Can you help me to learn more?

(Other definitions for nastiest that I've seen before include "Most revolting" , "Extremely unpleasant" .)

I've seen this clue in The Hindu.

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