Most of the coven unleash some malice (5)
I believe the answer is:
venom
'some malice' is the definition.
(synonyms)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for venom that I've seen before include "Toxic substance" , "Snake poison" , "Virulence" , "acrimony" , "Poison - spite" .)