Crossword Genius

Most relaxed ladies and gents maybe set out (7)

Ross

I believe the answer is:

loosest

'most relaxed' is the definition.
(I've seen this in another clue)

'ladies and gents maybe set out' is the wordplay.
'ladies and gents maybe' becomes 'loos' (toilets).
'out' indicates an anagram (out can mean wrong or inaccurate).
'set' is an anagram of 'est'.
'loos'+'est'='LOOSEST'

(Other definitions for loosest that I've seen before include "most unstable" , "most relaxed" .)

I've seen this clue in The Telegraph.
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