Mother is upset and angry (3)
I believe the answer is:
mad
'angry' is the definition.
(similar in meaning)
'mother is upset' is the wordplay.
'mother' becomes 'dam' (female parent of an animal).
'is upset' says the letters should be written in reverse (I've seen 'being upset' mean this).
'dam' in reverse letter order is 'MAD'.
'and' is the link.
(Other definitions for mad that I've seen before include "Crazy" , "Roused to anger" , "(Of a dog) rabid" , "lunatic" , "Frantic" .)