Mother with another female complaint (6)
I believe the answer is:
malady
'complaint' is the definition.
(malady is a kind of health problem)
'mother with another female' is the wordplay.
'mother' becomes 'ma' (Ma is another word for mother or mum).
'with' means one lot of letters go next to another.
'another female' becomes 'lady' (lady is a kind of female. I am not sure about the 'another' bit.).
'ma'+'lady'='MALADY'
Can you help me to learn more?
(Other definitions for malady that I've seen before include "Illness or disease" , "Disease, ailment" , "Afflication" , "Sickness, ailment" , "Disease or disorder" .)