Mother with mark, a make-up item (7)
I believe the answer is:
mascara
'make-up item' is the definition.
(I've seen this in another clue)
'mother with mark a' is the wordplay.
'mother' becomes 'ma' (Ma is another word for mother or mum).
'with' says to put letters next to each other.
'mark' becomes 'scar' (mark left by an injury).
'ma'+'scar'+'a'='MASCARA'
(Other definitions for mascara that I've seen before include "Cosmetic for the eyes" , "could be found in handbag, perhaps" , "Maracas (anag.)" , "that accentuates lashes" , "Make-up item" .)