Moving creation up as a safeguard (10)
I believe the answer is:
precaution
'a safeguard' is the definition.
(I know that safeguard can be written as precaution)
'moving creation up' is the wordplay.
'moving' indicates an anagram (letters are moved around).
'creation'+'up'='creationup'
'creationup' is an anagram of 'PRECAUTION'.
'as' acts as a link.
(Other definitions for precaution that I've seen before include "Safety measure" , "foresight" , "Measure taken in case it proves to be necessary" , "Advance measure taken against an undesirable development" , "Safeguard" .)