Muscle injury from run in country round Madrid (6)
I believe the answer is:
sprain
This clue could be a double definition.
'muscle injury' is the first definition.
'run in country round madrid' is the second definition.
'sprain' can be an answer for 'run' (thesaurus). I am not sure about the 'in country round madrid' bit.
'from' acts as a link.
Can you help me to learn more?
(Other definitions for sprain that I've seen before include "Wrench a joint" , "Minor muscular injury" , "unwelcome twist" , "Turn" , "Wrench (ligaments)" .)