Muse in sloop on Derwent (6)
I believe the answer is:
ponder
'muse' is the definition.
(I know that muse can be written as ponder)
'in sloop on derwent' is the wordplay.
'in' indicates the answer is hidden within the clue.
'PONDER' is hidden in the letters of 'sloop on derwent'.
(Other definitions for ponder that I've seen before include "Meditate, think deeply" , "Meditate - deliberate" , "Reflect" , "Think carefully" , "4 down" .)