Museo de América locale (6)
I believe the answer is:
madrid
'museo de america locale' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for madrid that I've seen before include "City with the Prado national art gallery" , "Spain's capital" , "Spanish city" , "European capital city" , "Capital of Spain since 1561" .)