Musical native not beginning to go west (5)
I believe the answer is:
evita
'musical' is the definition.
(Andrew Lloyd Webber musical)
'native not beginning to go west' is the wordplay.
'not beginning' means to remove the first letter.
'to go west' says the letters should be written in reverse (to go west can euphemistically mean to die).
'native' with its first letter taken away is 'ative'.
'ative' back-to-front is 'EVITA'.
(Other definitions for evita that I've seen before include "Well-known musical" , "Andrew Lloyd Webber musical set in Argentina" , "Peron musical" , "Eva Peron" , "1996 musical film, starring Madonna" .)