My agile, lean thoughtful leadership could be moonshine (4)
I believe the answer is:
malt
'could be moonshine' is the definition.
(moonshine refers to bootlegged alcohol)
'my agile lean thoughtful leadership' is the wordplay.
'leadership' says to take the initial letters.
The initial letters of 'my agile lean thoughtful' is 'MALT'.
(Other definitions for malt that I've seen before include "strong drink" , "Pure whisky" , "Grain product used in beer and whisky" , "Pre-soaked kiln-dried cereal grain" , "Barley product used in brewing" .)