My work on one article shows shortsightedness (6)
I believe the answer is:
myopia
'shortsightedness' is the definition.
('myopia' can be a synonym of 'shortsightedness')
'my work on one article' is the wordplay.
'work' becomes 'op' (abbreviation for opus**).
'on' is a charade indicator (letters next to each other).
'one' becomes 'i' (Roman numeral).
'article' becomes 'a' (indefinite article).
'my'+'op'+'i'+'a'='MYOPIA'
'shows' acts as a link.
(Other definitions for myopia that I've seen before include "vision problem" , "Short-sightedness" , "Seeing problem" , "Condition of short sightedness" , "Near-sightedness" .)