Mysteriously, Quixote's creator set off to find underground chamber (6)
I believe the answer is:
cavern
'underground chamber' is the definition.
(I've seen this before)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for cavern that I've seen before include "Subterranean chamber" , "Large dark hole in the ground" , "Detection device" , "vast enclosed space" , "Large underground chamber" .)