New pals in high places (4)
I believe the answer is:
alps
'high places' is the definition.
(I've seen this in another clue)
'new pals' is the wordplay.
'new' indicates an anagram.
'pals' with letters rearranged gives 'ALPS'.
'in' acts as a link.
(Other definitions for alps that I've seen before include "South-central European mountain system" , "Laps around mountains" , "high areas" , "Swiss mountains" , "Mont Blanc mountains" .)