New rate initially tempted nurse (5)
I believe the answer is:
treat
'nurse' is the definition.
(I've seen this before)
'new rate initially tempted' is the wordplay.
'new' indicates an anagram.
'initially' suggests taking the first letters.
The first letter of 'tempted' is 't'.
'rate' is an anagram of 'trea'.
'trea'+'t'='TREAT'
(Other definitions for treat that I've seen before include "Stand a drink" , "Event causing special pleasure" , "An indulgence; handle" , "Buy a drink for, for instance" , "Medicate" .)