Nice and saintly, but with very little heart (5)
I believe the answer is:
sweet
'nice' is the definition.
(both can mean agreeable or pleasant)
'saintly but with very little heart' is the wordplay.
I cannot quite see how this works, but
'with' could be 'w' (abbreviation) and 'w' is found in the answer.
'heart' could be 'see' (see is a kind of heart) and 'see' is found in the leftover letters.
A single letter 't' remains which might be clued in a way I don't see.
This may be the basis of the clue (or it may be nonsense).
'and' is the link.
Can you help me to learn more?
(Other definitions for sweet that I've seen before include "Pud" , "delightful" , "Candy item" , "Pudding" , "Sugary - but might be tart!" .)