Nice woman? (6)
I believe the answer is:
madame
'nice woman?' is the definition.
('woman' in French, eg in Nice)
'nice woman?' is the wordplay.
'nice' becomes 'mad' (I can't justify this - if you can you should give a lot more credence to this answer).
'woman?' becomes 'Ame'.
'mad'+'ame'='MADAME'
Can you help me to learn more?
(Other definitions for madame that I've seen before include "Woman of refinement" , "Flaubert novel" , "French Mrs" , "French married woman" , "Book by Flaubert" .)