Nightie e.g. in centre of bed, tangled with leg (8)
I believe the answer is:
negligee
'nightie' is the definition.
(I've seen this before)
'e g in centre of bed tangled with leg' is the wordplay.
'centre of' says to take the centre.
'tangled with' is an anagram indicator.
The central letter of 'bed' is 'e'.
'e'+'g'+'in'+'e'='egine'
'egine' with its letters anagrammed with 'leg' makes 'NEGLIGEE'.
(Other definitions for negligee that I've seen before include "informal attire" , "Woman's flimsy nightgown" , "Night shift" , "Loose flimsy garment" , "Female lace-trimmed garment" .)