Nightingale seen in Italian city (8)
I believe the answer is:
florence
I believe this is a double definition.
'nightingale' is the first definition.
(synonyms)
'italian city' is the second definition.
(city in Italy)
'seen in' acts as a link.
(Other definitions for florence that I've seen before include "famous Italian city" , "The familiar Miss Nightingale, famous nurse" , "Name of girl ? city" , "Italian city, noted art centre" , "Capital of Tuscany" .)