No longer globally relevant when asleep (4,2,3,5)
I believe the answer is:
dead to the world
'asleep' is the definition.
(thesaurus)
I don't understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for dead to the world that I've seen before include "Fast asleep" , "Sleeping" , "Sound asleep; unconscious" .)