No object in bothering Melissa (7)
I believe the answer is:
aimless
'no object in' is the definition.
Both the answer and definition are adjectives. Perhaps you can see an association between them that I can't see?
'bothering melissa' is the wordplay.
'bothering' indicates an anagram.
'melissa' is an anagram of 'AIMLESS'.
Can you help me to learn more?
(Other definitions for aimless that I've seen before include "Without direction or ambition" , "Melissa (anag) -- unmotivated" , "With no plan or programme" , "Without purpose, like Melissa" , "Without purpose or target" .)