No Sioux remedy is unpleasant (7)

I believe the answer is:

noxious

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'unpleasant' is the definition.
Both the answer and definition are adjectives. Maybe you can see a link between them that I don't see?

'no sioux remedy' is the wordplay.
'remedy' indicates an anagram (I've seen this in other clues).
'sioux' is an anagram of 'xious'.
'no'+'xious'='NOXIOUS'

'is' acts as a link.

Can you help me to learn more?

(Other definitions for noxious that I've seen before include "Unpleasant and harmful" , "Harmful, toxic" , "Pernicious" , "Harmful to health" , "foul" .)

I've seen this clue in The Irish Times.

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