Nobel prize-winner here begins novel (10)
I believe the answer is:
heisenberg
'nobel prize-winner' is the definition.
(physicist Werner Heisenberg, 1901-1976)
'here begins novel' is the wordplay.
'novel' indicates anagramming the letters (letters in a new or novel order).
'here'+'begins'='herebegins'
'herebegins' is an anagram of 'HEISENBERG'.
(Other definitions for heisenberg that I've seen before include "'Uncertainty principle' mathematical physicist, d. 1976 -- begins here (anag)" , "Nobel-winning physicist" , "Exact location and speed ever unknown, I suggested" , "to give name in uncertainty" , "Nobel prize-winner" .)