North African up in space (4)
I believe the answer is:
room
'space' is the definition.
(enough space or room to do something)
'north african up' is the wordplay.
'north african' becomes 'moor' (I've seen this in another clue).
'up' says the letters should be written in reverse (in down clue: letters go upwards).
'moor' reversed gives 'ROOM'.
'in' acts as a link.
(Other definitions for room that I've seen before include "See 17" , "Space within a building" , "Space; part of building" , "Enclosed part of building" , "Enclosed indoor space" .)