Not neutral on all occasions (5)
I believe the answer is:
never
'not' is the definition.
(thesaurus)
I can't explain the remainder of the clue.
Can you help me to learn more?
(Other definitions for never that I've seen before include "Strong negative" , "On no occasion" , "At no time in the past or future" , "when pigs fly" , "Surely not" .)