Not the gardener's favourite little number (4)

I believe the answer is:

weed

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'not the gardener's favourite' is the definition.
I can't tell whether this definition defines the answer.

'little number' is the wordplay.
'little' becomes 'wee' (similar in meaning).
'number' becomes 'd' (D is an example).
'wee'+'d'='WEED'

Can you help me to learn more?

(Other definitions for weed that I've seen before include "Hoe to remove it" , "Wild unwanted plant - tobacco?" , "Work in garden" , "pot" , "Got rid of water" .)

I've seen this clue in The Globe and Mail.

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