Not to close down at any time (5)
I believe the answer is:
never
'not' is the definition.
(thesaurus)
'close down at any time' is the wordplay.
'close down at' becomes 'n' (I can't explain this - if you can you should believe this answer much more).
'any time' becomes 'ever' (I've seen this in another clue).
'n'+'ever'='NEVER'
'to' acts as a link.
Can you help me to learn more?
(Other definitions for never that I've seen before include "Strong negative" , "Do not give up!" , "Under no circumstances" , "Surely not" , "No way" .)