Not willing to accept Republican way for America (10)
I believe the answer is:
interstate
'not willing to accept republican way for america' is the definition.
I can't judge whether this definition defines the answer.
'willing to accept republican way for america' is the wordplay.
I cannot quite understand how this works, but
'republican' could be 'r' (abbreviation in US politics) and 'r' is present in the answer.
'willing' could be 'testate' (I've seen this before) and 'testate' is located in the leftover letters.
'way' could be 'n' (Compass direction - North) and 'n' is found in the answer.
A single letter 'i' remains which might be clued in a way I don't see.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for interstate that I've seen before include "American way" , "road in US" , "between parts of US" , "highway" , "American motorway" .)
