Notes new centre for fashion (5)
I believe the answer is:
milan
'centre for fashion' is the definition.
(eg the annual Milan Fashion Week)
'notes new' is the wordplay.
'notes' becomes 'mi la' (mi and la are musical notes, as in do-re-mi).
'new' becomes 'n' (common abbreviation eg NT for New Testament).
'mila'+'n'='MILAN'
(Other definitions for milan that I've seen before include "Northern Italian city" , "province" , "N. Italian city" , "Italian industrial city" , "North Italian city" .)