Nothing found in ghastly premium shop (8)
I believe the answer is:
emporium
'shop' is the definition.
(I have seen 'Large shop' mean 'emporium' so perhaps 'shop' could also mean 'emporium')
'nothing found in ghastly premium' is the wordplay.
'nothing' becomes 'O' (O resembles 0).
'found in' indicates putting letters inside.
'ghastly' is an anagram indicator (a ghastly spelling of the words).
'premium' anagrammed gives 'emprium'.
'o' placed inside 'emprium' is 'EMPORIUM'.
(Other definitions for emporium that I've seen before include "Large and ostentatious retail establishment" , "Large department store" , "A large imposing shop" , "Large retail store with many departments" , "A large shop or centre of commerce" .)