Nothing like this one young lady, back from institute in Donegal, to have lark at The Centre (10)
I believe the answer is:
dissimilar
'this one young lady back from institute in donegal to have lark at the centre' is the definition.
Both the answer and definition are adjectives. Perhaps they are linked in a way I don't understand?
'nothing like' is the wordplay.
'nothing' becomes 'dis' (I am not sure about this - if you are sure you should believe this answer much more).
'like' becomes 'similar' ('similar' can be a synonym of 'like').
'dis'+'similar'='DISSIMILAR'
Can you help me to learn more?
(Other definitions for dissimilar that I've seen before include "Not like" , "Unlike" , "Unalike" .)