Nothing stops intense scream (4)
I believe the answer is:
hoot
'scream' is the definition.
(thesaurus)
'nothing stops intense' is the wordplay.
'nothing' becomes 'o' (looks like zero - 0).
'stops' is an insertion indicator.
'intense' becomes 'hot' ('hot' can be similar in meaning to 'intense'**).
'o' placed into 'hot' is 'HOOT'.
(Other definitions for hoot that I've seen before include "scream" , "Funny thing (informal);bird call" , "Bird call; funny thing" , "noise made by 7 [WOOD-OWL]" , "Warning sound - something not given by the careless!" .)