Now it includes men in anticipation of trouble (12)
I believe the answer is:
presentiment
'anticipation of trouble' is the definition.
'presentiment' can be an answer for 'anticipation' (thesaurus). I'm not certain of the 'of trouble' bit.
'now it includes men' is the wordplay.
'now' becomes 'present' (the present time).
'includes' indicates putting letters inside.
'it' going around 'men' is 'iment'.
'present'+'iment'='PRESENTIMENT'
'in' is the link.
Can you help me to learn more?
(Other definitions for presentiment that I've seen before include "Intuitive foreboding" , "Feeling of apprehension" , "bad feeling" , "An intuitive feeling" .)